Acquired Dyslexia Modeling and Treatment (NCT07209488)
🩺 Plain-English Summary (8th-Grade Level)
This study is a low-risk, early phase 1, multicenter trial to test the use of a computational (neural network) cognitive model of reading to simulate acquired dyslexia and its treatment. The aim is to determine whether there is an advantage to receiving the treatment the model predicts to be advantageous compared to the alternative treatment. All participants will receive two full rounds of treatment. A round of treatment will consist of either phonomotor treatment (PMT) or semantic feature analysis (SFA) for 60 hours, distributed over 5 days a week for 2 hours a day.
Who can join: To join this study, participants generally need to meet the listed inclusion criteria (5 items) and avoid the listed exclusions (5 items).
Location: Florida State University — Tallahassee, Florida
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistCheck every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).
Usually NOT eligible if any of the following apply:
- Exclusion Criteria:
- Diagnosed pre-stroke neurological disease affecting the brain other than left hemisphere stroke.
- Severe apraxia of speech (determined by consensus judgment among speech-language pathologists).
- History of learning disabilities such as developmental dyslexia or current self-reported major psychiatric disorders.
- Inability to undergo, or provide a copy of, a post-stroke brain imaging scan.
🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.
📍 All Participating Trial Locations (3 Sites)
- Florida State University — Tallahassee, Florida
- Johns Hopkins University School of Medicine — Baltimore, Maryland
- Kessler Foundation — West Orange, New Jersey
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.