Who is eligible for clinical trial NCT07217444?

Participants must meet protocol criteria for Major Depressive Disorder (MDD). Confirm exact inclusion and exclusion requirements with the study coordinator.

Does clinical trial NCT07217444 provide travel or cost reimbursement?

Check with the site coordinator at the participating facility for travel and lodging stipend availability, and for which routine-care costs are covered.

🏛️ Verified NIH Record • Updated 2026-02-10

Improving Outcomes in Adolescent Inpatient Depression With Deep Transcranial Magnetic Stimulation (NCT07217444)

🟢 Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol Sponsor: Children's Hospital Medical Center, Cincinnati

🩺 Plain-English Summary (8th-Grade Level)

Evaluate the feasibility, safety, and preliminary efficacy of deep Transcranial Magnetic Stimulation (dTMS) as an adjunctive treatment for adolescents hospitalized with major depressive disorder (MDD).

Who can join: To join this study, participants generally need to meet the listed inclusion criteria (5 items) and avoid the listed exclusions (6 items).

Location: Cincinnati Childrens Hospital Medical Center — Cincinnati, Ohio

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Check every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).

Fluent in English and able to volunteer in the informed consent process and provide spontaneous narrative description of key elements, risks, and benefits of the study.
Aged 14 years to 18 years, inclusive.
Diagnosis of MDD based on psychologist diagnosis and DSM-5-checklist based interview.
Symptoms of moderate to severe depression according to Hamilton Depression Rating Scale Score \> 20.
Participants are not required to discontinue current interventions

Usually NOT eligible if any of the following apply:

Exclusion Criteria:
Participation in an investigational drug trial within the past three months.
Contraindications to Transcranial Magnetic Stimulation including, but not limited to, a history of epilepsy, the presence of metallic foreign bodies, or implanted medical devices (e.g. ventriculoperitoneal shunt, pacemaker, medical pump).
Actively psychotic (i.e. disorganized, delusional, paranoid, or having hallucinations)
Actively suicidal (have a suicidal plan and intent and is on 1:1 close observation)
For female subjects of childbearing potential, a positive urine pregnancy test.

🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.

📍 All Participating Trial Locations (1 Sites)

Cincinnati Childrens Hospital Medical Center — Cincinnati, Ohio

💰 Cost, Insurance & Patient Rights

100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

🏛️ View Official NIH Record ↗