A Phase III Trial of BNT324 Versus Docetaxel in Metastatic Castration-resistant Prostate Cancer (NCT07365995)
🩺 Plain-English Summary (8th-Grade Level)
This study will test whether BNT324 is safe and works better against metastatic castration-resistant prostate cancer (mCRPC) than the current standard of care (SoC) chemotherapy, which is docetaxel (given together with the steroid medicines prednisone or prednisolone). The study will include participants with mCRPC that have been previously treated with androgen receptor pathway inhibitor, but with no previous taxane-based systematic chemotherapy for mCRPC. The main goals of this study are: * To find out if BNT324 helps participants live longer without their cancer getting worse (radiographic progression-free survival \[rPFS\]). * To find out if BNT324 helps participants live longer overall (overall survival \[OS\]).
Who can join: Review the eligibility criteria below.
Location: Rocky Mountain Cancer Centers — Aurora, Colorado
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (15 Sites)
- Rocky Mountain Cancer Centers — Aurora, Colorado
- Florida Cancer Specialists- Fort Myers — Fort Myers, Florida
- Florida Cancer Specialists- St. Petersburg — St. Petersburg, Florida
- Florida Cancer Specialists- West Palm Beach — West Palm Beach, Florida
- Illinois Cancer Specialists — Niles, Illinois
- Illinois CancerCare PC — Peoria, Illinois
- Maryland Oncology Hematology — Rockville, Maryland
- Oncology/Hematology Care, Inc. — Cincinnati, Ohio
- SCRI Oncology Partners — Nashville, Tennessee
- Texas Oncology South Austin — Austin, Texas
- Texas Oncology Gulf Coast — Houston, Texas
- Texas Oncology, P.A. - Tyler — Tyler, Texas
- Texas Oncology - West Texas — Wichita Falls, Texas
- Virginia Cancer Specialists PC — Fairfax, Virginia
- Virginia Oncology Associates — Norfolk, Virginia
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.