🏛️ Verified NIH Record • Updated 2026-06-29
Study of Efficacy and Safety of Tonlamarsen in Participants With a Recent Hospitalization and a Concurrent Episode of Acute Severe Hypertension (NCT07511361)
🟢 Recruiting Phase2 💊 Investigational Drug / Biologic Sponsor: Kardigan, Inc.
🩺 Plain-English Summary (8th-Grade Level)
The purpose of this study is to evaluate the blood pressure-lowering effect of tonlamarsen in adult participants who were recently hospitalized and concurrently experienced an episode of acute severe hypertension.
Who can join: Review the eligibility criteria below.
Location: Western Nephrology and Metabolic Bone Disease, PC - Arvada — Arvada, Colorado
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (8 Sites)
- Western Nephrology and Metabolic Bone Disease, PC - Arvada — Arvada, Colorado
- Homestead Associates in Research — Homestead, Florida
- Progressive Medical Research — Port Orange, Florida
- Richmond University Medical Center (RUMC) — Staten Island, New York
- Research Innovations, LLC — Beavercreek, Ohio
- Chattanooga Research & Medicine CHARM — Chattanooga, Tennessee
- Laguna Clinical Research Associates — Laredo, Texas
- Baylor Scott and White Research Institute - Temple — Temple, Texas
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.