🏛️ Verified NIH Record • Updated 2026-07-31
PRESERVE: LUPKYNIS in Combination With Belimumab, Obinutuzumab or Anifrolumab in Patients With Lupus Nephritis (NCT07611214)
🟢 Recruiting Phase4 💊 Investigational Drug / Biologic Sponsor: Aurinia Pharmaceuticals Inc.
🩺 Plain-English Summary (8th-Grade Level)
The goal of this clinical study is to assess the efficacy and safety of LUPKYNIS® in combination with belimumab, obinutuzumab or anifrolumab at inducing rapid renal response in patients with lupus nephritis (LN).
Who can join: Review the eligibility criteria below.
Location: Purushotham & Akther Kotha MD, Inc. — La Mesa, California
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (27 Sites)
- Purushotham & Akther Kotha MD, Inc. — La Mesa, California
- Valerius Medical Group & Research Center of Greater Long Beach, Inc. — Los Alamitos, California
- Western Nephrology & Metabolic Bone Disease, PC — Arvada, Colorado
- Swati Shah MD Rheumatology, LLC — Jacksonville, Florida
- Vida Clinical Research — Kissimmee, Florida
- Life Clinical Trials — Margate, Florida
- CTR Oakwater — Orlando, Florida
- Parris and Associates Rheumatology — Lawrenceville, Georgia
- Accurate Clinical Research, Inc. — Lake Charles, Louisiana
- Arthritis and Rheumatism Associates — Rockville, Maryland
- Kansas City Physician Partners — Kansas City, Missouri
- University of Nevada Las Vegas — Las Vegas, Nevada
- Sahni Rheumatology & Therapy — West Long Branch, New Jersey
- Buffalo Rheumatology and Medicine, PLLC — Orchard Park, New York
- Arthritis and Osteoporosis Consultants of the Carolinas — Charlotte, North Carolina
- Joint and Muscle Research Institute — Charlotte, North Carolina
- Rheumatic Disease Associates, Ltd. — Willow Grove, Pennsylvania
- Dunes Clinical Research — Dakota Dunes, South Dakota
- West Tennessee Research Institute — Jackson, Tennessee
- Novel Research LLC — Bellaire, Texas
- Liberty Research Center — Dallas, Texas
- Texas Arthritis Center — El Paso, Texas
- Integrative Rheumatology of South Texas — Harlingen, Texas
- Northwest Houston Arthritis Center — Houston, Texas
- Texas Tech University Health Science Center — Lubbock, Texas
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.