Who is eligible for clinical trial NCT07763418?

Participants must meet protocol criteria for Kidney Failure, Chronic. Confirm exact inclusion and exclusion requirements with the study coordinator.

Does clinical trial NCT07763418 provide travel or cost reimbursement?

Check with the site coordinator at the participating facility for travel and lodging stipend availability, and for which routine-care costs are covered.

🏛️ Verified NIH Record • Updated 2026-08-10

A Study to Evaluate the Pharmacokinetics and Safety of Golcadomide in Participants With Severe Renal Impairment and End-Stage Renal Disease Compared With Participants With Normal Renal Function (NCT07763418)

🟡 Not Yet Recruiting Phase1 💊 Investigational Drug / Biologic Sponsor: Bristol-Myers Squibb

🩺 Plain-English Summary (8th-Grade Level)

The purpose of this study is to assess the pharmacokinetics and safety of golcadomide (BMS-986369) in matched healthy participants with normal renal function, adult participants with severe renal impairment, and participants with end-stage renal disease.

Who can join: To join this study, participants generally need to meet the listed inclusion criteria (3 items) and avoid the listed exclusions (5 items).

Location: Local Institution - 0003 — Chandler, Arizona

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Check every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).

Participant must have severe renal impairment (RI).
Participant must have end-stage renal disease (ESRD).
Participant must be healthy male and female participants not of childbearing potential between 18 and 84 years of age (inclusive) with a BMI between 18 and 40 kg/m2, (inclusive) at screening.

Usually NOT eligible if any of the following apply:

Exclusion Criteria:
Any surgical or medical condition possibly affecting drug absorption, distribution, metabolism, and excretion (ADME).
Any significant medical condition, laboratory abnormality, or psychiatric illness that would prevent the participant from participating in the study
Known or suspected active autoimmune disorder, or any history of known or suspected congenital or acquired immunodeficiency state or condition that would compromise the participant's immune status
Other protocol-defined inclusion/exclusion criteria apply.

🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.

📍 All Participating Trial Locations (3 Sites)

Local Institution - 0003 — Chandler, Arizona
Local Institution - 0002 — Miami Lakes, Florida
Local Institution - 0001 — Orlando, Florida

💰 Cost, Insurance & Patient Rights

100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

🏛️ View Official NIH Record ↗