100 Recruiting Studies at Johns Hopkins Medicine
Active clinical trials at this research center, sourced directly from the NIH registry.
📍 Baltimore, Maryland
All research centersRecruiting Studies at Johns Hopkins Medicine
🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic
Study of Rituximab or Tocilizumab for Patients With Steroid-Dependent Immune-Related Adverse Events (irAEs)
Immune-related Adverse Events
View Study & Checklist ➔ 🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research
Ultra High Resolution CT to Assess Role of Intramyocardial Fat and Delayed Enhancement in Ventricular Arrhythmogenesis
Ventricular Arrhythmias
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase4 💊 Investigational Drug / Biologic
C-Raven, a Virtual Tobacco Cessation Intervention in Residency Clinics
Tobacco Dependence
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic
Neoadjuvant Enoblituzumab (MGA271) in Men With Localized Intermediate and High-Risk Prostate Cancer
Prostate Cancer
View Study & Checklist ➔ 🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research
Novel Biomarkers in the Neoplastic Progression of Barrett's Esophagus
Barrett Esophagus
View Study & Checklist ➔ 🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research
Multi-parametric Biomarker Development to Predict Malignant Conversion in Patients With Neurofibromatosis Type 1
Neurofibromatosis 1
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic
Trial of Dichloroacetate (DCA) in Glioblastoma Multiforme (GBM)
Glioblastoma Multiforme
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic
Boost GVAX Pancreas Vaccine With or Without CY in Patients With Pancreas Cancer
Pancreatic Cancer
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase1 / Phase2 💊 Investigational Drug / Biologic
Safety and Efficacy of EcoActive on Intestinal Adherent Invasive E. Coli in Patients With Inactive Crohn's Disease
Crohn Disease
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program
Preventing Postpartum Depression in Immigrant Latinas
Postpartum Depression
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic
Study of Zelenectide Pevedotin in Participants With Advanced Breast Cancer
Breast Cancer
View Study & Checklist ➔ 🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research
Assessment of Remote Vital Signs for Telemedicine Applications
Telemedicine
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase1 / Phase2 💊 Investigational Drug / Biologic
REACTION (Radiation Enhanced Assessment of Combination Therapies in Immuno-ONcology) - Nivolumab or Nivolumab in Combination With Other Immuno-oncology (IO) Agents After Targeted Systemic Radiation in Patients With Advanced Esophagogastric Cancer
Gastroesophageal Cancer
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic
AG-120 in People With IDH1 Mutant Chondrosarcoma
Chondrosarcoma
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program
Clinic-based HIV Identification and Prevention Project Using Electronic Resources
HIV Prevention
View Study & Checklist ➔ ACTIVE_NOT_RECRUITING Interventional Protocol 📊 Observational Clinical Research
Addressing Post-Intensive Care Syndrome Among Survivors of COVID (APICS-COVID)
Post Intensive Care Syndrome
View Study & Checklist ➔ 🔵 Active, Not Recruiting Early Phase1 💊 Investigational Drug / Biologic
Effect of Topical Sulforaphane on Skin Aging and With Ultraviolet and Visible Light Exposure
Skin Aging
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program
Peer Supported Collaborative Care Mental Health and Substance Use Disorder Care
HIV Infections
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program
Pathways to Improved Adolescent Mental Health in Conflict Affected Families
Mental Health Issue
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program
Digital Literacy Intervention to Address Support, Literacy and Communication in Older Adults
Quality of Life
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic
Nivolumab +/- Relatlimab Prior to Chemoradiation With II/III Gastro/Esophageal Cancer
Gastric Cancer
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic
Platform Study of Neoadjuvant and Adjuvant Immunotherapy for Patients With Resectable Adenocarcinoma of the Pancreas
Pancreatic Cancer
View Study & Checklist ➔ 🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research
Novel Antineuronal Antibodies in Gastrointestinal Motility Disorders
Autoimmune Gastrointestinal Dysmotility
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase1 / Phase2 💊 Investigational Drug / Biologic
Study of Nivolumab and Axitinib in Patients With Advanced Renal Cell Carcinoma
Renal Cell Carcinoma
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic
A Study of Psilocybin for PTSD
Post Traumatic Stress Disorder
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 💊 Investigational Drug / Biologic
Reduced Opioid Prescription After Laparoscopic Hysterectomy
Pain, Postoperative
View Study & Checklist ➔ 🔵 Active, Not Recruiting Early Phase1 💊 Investigational Drug / Biologic
Effects of Psilocybin in Obsessive Compulsive Disorder
Obsessive-Compulsive Disorder
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol
Multichannel Vestibular Implant Early Feasibility Study
Other Disorders of Vestibular Function, Bilateral
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 🩺 Clinical Procedure Protocol
Prone Positioning During Delayed Cord Clamping
Delayed Cord Clamping
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic
Intravesical Gemcitabine and Docetaxel for BCG naïve Non-muscle Invasive Bladder Cancer
Urothelial Carcinoma Bladder
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol
Wearable Insoles for Recurrent Diabetic Ulcer Prevention
Diabetes
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase1 📋 Clinical Research Protocol
Intraoperative Radiation Therapy After Stereotactic Body Radiation Therapy and Chemotherapy in Treatment of Pancreatic Adenocarcinoma
Pancreatic Cancer
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol
Music and Brain Stimulation for Upper Extremity Performance in Patients With Corticobasal Syndrome
Corticobasal Syndrome
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic
Palbociclib With Fulvestrant for Metastatic Breast Cancer After Treatment With Palbociclib and an Aromatase Inhibitor
Metastatic Breast Cancer
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program
Whole-Food Plant-Based Diet to Control Weight and MetaboInflammation in Overweight/Obese Men With Prostate Cancer
Prostate Cancer
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic
STEMVAC in Patients With Early Stage Triple Negative Breast Cancer
Anatomic Stage IB Breast Cancer AJCC v8
View Study & Checklist ➔ 🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research
Impact of Ketogenic Diets on Cardiovascular Health in Adults With Epilepsy
Hypercholesterolemia
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic
Psilocybin Treatment of Major Depressive Disorder With Co-occurring Alcohol Use Disorder
Major Depressive Disorder
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase3 💊 Investigational Drug / Biologic
Behavioral Pharmacological Examination of a Novel Buprenorphine Induction Method Among Individuals Who Use Fentanyl
Opioid Use Disorder
View Study & Checklist ➔ 🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research
Cervical Paraspinal Muscle Twitching and Cervical Facet Radiofrequency Ablation Outcomes
Cervical Facet Joint Pain
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program
Developing a Learning COmmunity to Increase eNgagemeNt and Enrollment in Cardiovascular Clinical Trials (CONNECT)
Cardiovascular Diseases
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program
Behavioral Weight Loss for Cancer Survivors in Maryland: A Trial With Adaptive Interventions
Weight Loss
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic
Effects of Simvastatin on Uterine Leiomyoma Size
Fibroid Uterus
View Study & Checklist ➔ 🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research
Patient Response to Immunotherapy Using Spliceosome Mutational Markers (PRISMM)
Metastatic Solid Tumor
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program
Technology Based Community Health Nursing(TECH-N) to Prevent Recurrent STIs After PID II
Pelvic Inflammatory Disease
View Study & Checklist ➔ 🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research
A Multi-Modal Remote Monitoring Platform for Frontotemporal Lobar Degeneration (FTLD) Syndromes
PSP
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic
Olaparib in Men With High-Risk Biochemically-Recurrent Prostate Cancer Following Radical Prostatectomy, With Integrated Biomarker Analysis
Prostate
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase1 / Phase2 💊 Investigational Drug / Biologic
GNOS-PV02 Personalized Neoantigen Vaccine, INO-9012 and Pembrolizumab in Subjects With Advanced HCC
HCC
View Study & Checklist ➔ 🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research
The Very Large Database of Lipids
Lipid Disorders and Lipid Measurement
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program
The Sedentary to Active Rising to Thrive (START) Trial
Sedentary Time
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase1 / Phase2 💊 Investigational Drug / Biologic
Safety and Efficacy of Allogeneic HPV-specific T Cells in Adults With Recurrent or Metastatic HPV16+ Cancers
HPV 16+ Recurrent or Metastatic Cancer
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic
Itacitinib With High-dose Posttransplantation Cyclophosphamide in Older Patients
Leukemia, Acute
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic
Neoadjuvant Targeting of Myeloid Cell Populations in Combination With Nivolumab in Head & Neck Ca
Head and Neck Squamous Cell Carcinoma
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic
A Neoadjuvant Study of Tislelizumab and SX-682 for Resectable Pancreas Cancer
Pancreatic Cancer
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
PICU Up!: A Pilot Stepped-wedge Trial of a Multicomponent Early Mobility Intervention for Critically Ill Children
Critical Illness
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic
Feasibility and Safety Study of Parent-to-Child Nasal Microbiota Transplant
Staphylococcus Aureus
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol
Fetoscopic Endoluminal Tracheal Occlusion (FETO) for Severe Left Diaphragmatic Hernia (CDH)
Congenital Diaphragmatic Hernia
View Study & Checklist ➔ 🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research
Medication Adherence in Patients With Sarcoidosis
Medication Adherence
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic
FIGHT-RP 1 Extension Study
Retinitis Pigmentosa
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol
Fetoscopic Repair of Isolated Fetal Spina Bifida
Spina Bifida
View Study & Checklist ➔ 🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research
Percutaneous Cholangiopancreatoscopy Registry
Biliary Stones
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic
A Study of the Treatment of Recurrent Malignant Glioma With rQNestin34.5v.2
Malignant Glioma of Brain
View Study & Checklist ➔ ACTIVE_NOT_RECRUITING Phase1 / Phase2 💊 Investigational Drug / Biologic
A Study of Blinatumomab in Patients With Pre B-cell ALL and B-cell NHL as Post-allo-HSCT Remission Maintenance
Acute Lymphoblastic Leukemia
View Study & Checklist ➔ 🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research
PaTH Clinical Data Research Network (CDRN) Study of Healthy Lifestyles and Health Care
Weight
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program
Strong Heart Water Study
Arsenic Poisoning
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic
Vorinostat and Azacitidine in Treating Patients With Locally Recurrent or Metastatic Nasopharyngeal Cancer or Nasal Natural Killer T-Cell Lymphoma
Adult Nasal Type Extranodal NK/T-Cell Lymphoma
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
Using Personalized Assessments in the Treatment of Childhood OCD
Obsessive-Compulsive Disorder
View Study & Checklist ➔ 🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research
Johns Hopkins Breast Cancer Program Longitudinal Repository
Breast Cancer
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic
ABA-101 in Participants With Progressive Multiple Sclerosis
Progressive Multiple Sclerosis
View Study & Checklist ➔ 🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research
Long Term Outcomes of Bariatric Patients Treated With Surgery or Endoscopy
GERD
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic
Evaluate the Safety, Immunologic, and Virologic Responses of Donor Derived (DD) HIV-Specific T-cells (HST) in HIV-infected Individuals Following Allogeneic Bone Marrow Transplantation (alloRESIST)
HIV-Infected Individuals
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program
Stepped Care for Weight Loss Maintenance
Obesity
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program
Using CBPR to Engage Hazardous Drinking Women in the HIV Prevention and Care Continuum
HIV
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
Personalized Molecular Profiling in Cancer Treatment at Johns Hopkins
Metastatic Breast Cancer
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
Gracie Diet for Gastroesophageal Reflux Disease
Gastroesophageal Reflux
View Study & Checklist ➔ 🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research
Natural History Study of Cutaneous Neurofibromas in People With NF1
Neurofibromatosis Type 1
View Study & Checklist ➔ 🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research
PaTH Clinical Data Research Network (CDRN) Atrial Fibrillation (AF) Clinician-Patient Partnership Cohort
Atrial Fibrillation
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic
The Prevention of Progression to Pancreatic Cancer Trial (The 3P-C Trial)
IPMN
View Study & Checklist ➔ 🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research
Validation of ClarityDX Prostate as a Reflex Test to Refine the Prediction of Clinically-significant Prostate Cancer
Prostate Cancer
View Study & Checklist ➔ 🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research
Johns Hopkins Crohn's Disease and Ulcerative Colitis Study
Inflammatory Bowel Disease
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic
Peripheral Modulation of Muscle Stiffness and Spasticity
Muscle Spasticity
View Study & Checklist ➔ 🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research
Physical Activity, Cardiac and Skeletal Muscle Energetics in Healthy Subjects and HFpEF Patients
Heart Failure With Preserved Ejection Fraction
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic
Nivolumab With or Without Stereotactic Radiosurgery in Treating Patients With Recurrent, Advanced, or Metastatic Chordoma
Chordoma
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol
Effects of Electrical Stimulation on Verbal Learning in Typical and Atypical Alzheimer's Disease
Alzheimer Disease, Early Onset
View Study & Checklist ➔ 🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research
PaTH Clinical Data Research Network (CDRN) Idiopathic Pulmonary Fibrosis (IPF) Clinician Patient Partnership Cohort
Idiopathic Pulmonary Fibrosis
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol
Optic Nerve Head Strain as Biomarker for Glaucoma
Glaucoma, Open-Angle
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic
Neoadjuvant Nivolumab, or Nivolumab in Combination With Ipilimumab, in Resectable NSCLC
Non-Small Cell Lung Cancer
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic
Vorinostat Dose-escalation After Allogeneic Hematopoietic Cell Transplantation
Acute Myeloid Leukemia
View Study & Checklist ➔ 🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research
Multi-Center African-American Inflammatory Bowel Disease Study (MAAIS)
Inflammatory Bowel Disease
View Study & Checklist ➔ 🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research
Men and Women Offering Understanding of Throat HPV
Oropharyngeal Cancer
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase2 ⚙️ Medical Device Protocol
The PRECISION Trial (Profiling Early Breast Cancer for Radiotherapy Omission): A Phase II Study of Breast-Conserving Surgery Without Adjuvant Radiotherapy for Favorable-Risk Breast Cancer
Breast Cancer Radiation
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic
Determinants of Resistance to Endocrine Therapy and a Cyclin-dependent Kinases 4 and 6 (CDK4/6) Inhibitor for HR+ MBC
Breast Cancer
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
MRI for Assessing Prostate Cancer Response
Prostate Cancer
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic
Ketamine for Multiple Sclerosis Fatigue
Multiple Sclerosis Fatigue
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic
Selpercatinib Before Surgery for the Treatment of RET-Altered Thyroid Cancer
Malignant Thyroid Gland Neoplasm
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase3 📋 Clinical Research Protocol
ACHIEVE Brain Health Follow-Up Study
Aging
View Study & Checklist ➔ 🟡 Not Yet Recruiting Interventional Protocol 📊 Observational Clinical Research
Remote Monitoring in Progressive Supranuclear Palsy (PSP)
Progressive Supranuclear Palsy
View Study & Checklist ➔ 🟡 Not Yet Recruiting Phase1 💊 Investigational Drug / Biologic
A DNAJB1-PRKACA Fusion Kinase Peptide Vaccine Combined With Glutamine Antagonist DRP-104, Nivolumab, and Ipilimumab in Patients With Advanced Stage Fibrolamellar Carcinoma (FLC)
Liver Cancer (Fibrolamellar Hepatocellular Cancer (FLC))
View Study & Checklist ➔ 🟡 Not Yet Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol
The Use of a FDA Cleared, Drug-free, Breathing System for Anxiety and Panic Disorders in Children and Teens
Anxiety
View Study & Checklist ➔ 🟡 Not Yet Recruiting Phase2 💊 Investigational Drug / Biologic
PSMA-High: EBRT/ PSMA617/ ADT vs. EBRT/ ADT
High-Risk Localized Prostate Cancer
View Study & Checklist ➔