100 Recruiting Studies at Northwestern Medicine

Active clinical trials at this research center, sourced directly from the NIH registry.

📍 Chicago, Illinois

All research centers

Recruiting Studies at Northwestern Medicine

🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program

Vaccine Hesitancy in Black/African Americans With Rheumatic Diseases

Rheumatic Diseases

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🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic

Study of MK-0472 in Participants With Advanced/Metastatic Solid Tumors (MK-0472-001)

Metastatic Solid Tumors

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🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program

Basic Experimental Study of Hippocampal Memory Functions

Memory

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🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program

Impact of Resilience Training on Quality of Life in New Ostomy Patients and Their Partners

Ileostomy - Stoma

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

Platelet-rich Plasma for Eyebrows

Eyebrow Hypotrichosis

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

Pembrolizumab and Tazemetostat to Overcome Immune Tolerance Following ASCT or CAR T-cell Therapy in Patients With Aggressive B-Cell Non-Hodgkin's Lymphoma

B-Cell Non-Hodgkin Lymphoma

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🔵 Active, Not Recruiting Phase3 💊 Investigational Drug / Biologic

Optimizing Tobacco Use Treatment for PLWHA

HIV/AIDS

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🔵 Active, Not Recruiting Early Phase1 💊 Investigational Drug / Biologic

A Pilot Study Testing Onabotulinum Toxin A Versus Incobotulinum Toxin A Injections for Facial Wrinkles

Wrinkles

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🔵 Active, Not Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol

Positioning for Hip Arthroscopic Surgery to Reduce Postoperative Numbness

Hip Osteoarthritis

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

Clinical Study of Neflamapimod in Patients With Primary Progressive Aphasia

Nonfluent Variant Primary Progressive Aphasia (nfvPPA)

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🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research

Skin Elasticity Measurements of the Face and Surgical Scars Stratified by Age and Skin Type

Skin Scarring

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🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program

Expanding Live Donor Kidney Transplantation Through Advocacy Training and Social Media

Kidney Failure

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🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic

Nivolumab, BMS-986205, and Radiation Therapy With or Without Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma

Glioblastoma

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🔵 Active, Not Recruiting Phase3 💊 Investigational Drug / Biologic

Dronabinol After Arthroscopic Surgery

Knee Osteoarthritis

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🔵 Active, Not Recruiting Observational / Diagnostic 📋 Clinical Research Protocol

A Pilot Study Testing Salicylic Acid Peels Versus Glycolic Acid Peels for the Treatment of Melasma

Melanosis

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🔵 Active, Not Recruiting Observational / Diagnostic 🩺 Clinical Procedure Protocol

Ureteroscopy With High-powered Holmium:Yag Laser Lithotripsy With and Moses On or Moses Off

Kidney Stone

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🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic

Mycophenolate Mofetil in Combination With Standard of Care for the Treatment of Glioblastoma

Astrocytoma

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🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program

Encouraging Multiple PrEP Options for Women Engaged in PRimary Care

PrEP Education

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🔵 Active, Not Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol

Effect of Duramesh™ on Hernia Formation After Ileostomy Closure

Incisional Hernia

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

Zanubrutinib and CAR T-cell Therapy for the Treatment of Recurrent or Refractory Aggressive B-cell Non-Hodgkin's Lymphoma or Transformed Indolent B-cell Lymphoma

Diffuse Large B-Cell Lymphoma Associated With Chronic Inflammation

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🔵 Active, Not Recruiting Observational / Diagnostic 📋 Clinical Research Protocol

A Multimedia Presentation to Augment the Informed Consent Process for Anesthesia for Patients Undergoing Scheduled Caesarian Delivery

Pregnancy

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

Combination Therapy With Entinostat and Pembrolizumab in Relapsed and Refractory Lymphomas

Lymphoma

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🔵 Active, Not Recruiting Observational / Diagnostic 📋 Clinical Research Protocol

Mobile Health Interventions to Prevent Heart Disease After Hypertensive Disorders of Pregnancy

Hypertension in Pregnancy

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

A Study With L19TNF in Combination With Lomustine in Patients With Glioblastoma at Progression or Recurrence

Glioblastoma

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🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research

Artificial Intelligence Patient App for RDEB SCCs

Epidermolysis Bullosa Dystrophica

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🔵 Active, Not Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol

Dose Escalation Study Evaluating Safety of TheraSphere Prostate Cancer (PCa) Device

Prostate

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🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program

Effectiveness and Implementation of Text Messaging to Improve HIV Testing in Adolescents

HIV

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🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program

Knee Arthroplasty Activity Trial

Knee Osteoarthritis

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🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program

Voice Activated Personal Assistant for Depression Among Older Adults

Depression, Anxiety

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🔵 Active, Not Recruiting Phase1 / Phase2 💊 Investigational Drug / Biologic

Gedatolisib Plus Talazoparib in Advanced Triple Negative or BRCA1/2 Positive, HER2 Negative Breast Cancers

TNBC - Triple-Negative Breast Cancer

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🔵 Active, Not Recruiting Phase4 💊 Investigational Drug / Biologic

Treatment of Facial Flushing With Botulinum Toxin A Injections

Facial Flushing

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🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic

Nintedanib and Azacitidine in Treating Participants With HOX Gene Overexpression Relapsed or Refractory Acute Myeloid Leukemia

Acute Myeloid Leukemia With t(9;11)(p22.3;q23.3); MLLT3-KMT2A

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🔵 Active, Not Recruiting Phase4 💊 Investigational Drug / Biologic

Study of Nonsteroidal Anti-inflammatory Drugs in People With Painful Knee Osteoarthritis

Osteoarthritis, Knee

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🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic

Testing the Combination of the Anti-cancer Drugs XL184 (Cabozantinib) and Nivolumab in Patients With Advanced Cancer and HIV

Advanced Differentiated Thyroid Gland Carcinoma

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

Vistusertib (AZD2014) For Recurrent Grade II-III Meningiomas

Meningioma

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🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program

Perinatal Depression and Adverse Childhood Experiences: Prevention Trial

Perinatal Depression

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🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program

Behavioral Nudges for Diabetes Prevention (BEGIN) Trial in Primary Care

PreDiabetes

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

CHIO3 Trial: CHemotherapy Combined With Immune Checkpoint Inhibitor for Operable Stage IIIA/B Non-Small Cell Lung Cancer

Stage IIIA Non-small Cell Lung Cancer

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🔵 Active, Not Recruiting Observational / Diagnostic 💊 Investigational Drug / Biologic

Methocarbamol vs Oxybutynin for Management of Pain and Discomfort S/P Ureteroscopy Procedure

Kidney Calculi

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🔵 Active, Not Recruiting Phase3 🧠 Behavioral & Psychological Program

Web-based Pain Coping Skills Training for Breast Cancer Survivors With AI-Associated Arthralgia

Breast Cancer

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🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research

Evaluation of a Collaborative Behavioral Health Program Implementation in Primary Care

Depression

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🔵 Active, Not Recruiting Observational / Diagnostic 🩺 Clinical Procedure Protocol

Cyrolipolysis vs Cyrolipolysis and Subcision for Cellulite

Cellulite

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🔵 Active, Not Recruiting Observational / Diagnostic 📋 Clinical Research Protocol

Stepping to Understand Lower Limb Impairments in Bilateral Cerebral Palsy

Cerebral Palsy

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🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic

Intraventricular Administration of Rhenium-186 NanoLiposome for Leptomeningeal Metastases

Leptomeningeal Metastasis

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🔵 Active, Not Recruiting Observational / Diagnostic 💊 Investigational Drug / Biologic

Potassium Citrate and Crystal Light Lemonade

Kidney Stone

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🔵 Active, Not Recruiting Phase3 💊 Investigational Drug / Biologic

Study of Efficacy and Safety of Dabrafenib in Combination With Trametinib in Previously Treated Patients With Metastatic, Radio-active Iodine Refractory BRAF V600E Mutation Positive Differentiated Thyroid Cancer

Differentiated Thyroid Cancer (DTC)

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🔵 Active, Not Recruiting Phase1 ⚙️ Medical Device Protocol

A Pilot Study Testing a Noninvasive Cryolipolysis Device Versus a High Intensity Focused Ultrasound Device for Fat Reduction

Abdominal Fat

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🔵 Active, Not Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol

Intermittent Pneumatic Compression With and Without Exercise to Improve Functioning in Peripheral Artery Disease

Peripheral Artery Disease

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

Androgen Deprivation Therapy (ADT) and Pembrolizumab for Advanced Stage Androgen Receptor-positive Salivary Gland Carcinoma

Salivary Gland Carcinoma

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

Testing Atorvastatin to Lower Colon Cancer Risk in Longstanding Ulcerative Colitis

Colorectal Carcinoma

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🔵 Active, Not Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol

Continued Access Study to Evaluate Performance of the Organ Recovery Systems _LifePort® Liver Transporter System, a Machine Perfusion System, for Liver Transplant (PILOT™_CA)

Liver Transplantation

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🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program

The Study in Outpatient Medicine Using Nudges to Improve Sleep

Inappropriate Prescribing

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🔵 Active, Not Recruiting Phase1 / Phase2 💊 Investigational Drug / Biologic

Combining Ipilimumab With Abiraterone Acetate Plus Prednisone in Chemotherapy and Immunotherapy-naïve Patients With Progressive Metastatic Castration-resistant Prostate Cancer

Prostate Cancer

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

Topical Afimoxifene in Treating Patients With Breast Cancer Who Have Undergone Radiation Therapy on One Breast

Cancer Survivor

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🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research

MRI And GPS Informing Choices for Prostate Cancer Treatment (MAGIC)

Prostate Cancer

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🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research

Quality of Life in Pre and Post Renal Transplant in Hispanic and Non-Hispanic Recipients

Transplant; Failure, Kidney

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🔵 Active, Not Recruiting Early Phase1 💊 Investigational Drug / Biologic

PET/MRI for the Staging of Newly Diagnosed Prostate Cancer

Prostate Cancer

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

Adjuvant Treatment With Cisplatin-based Chemotherapy Plus Concomitant Atezolizumab in Patients With Stage I (Tumors ≥ 4cm), IIA, IIB, and Select Stage III [Any T1-3 N1-2 and T4N0-2] Resected Non-small Cell Lung Cancer (NSCLC) and the Clearance of Circulating Tumor DNA (ctDNA)

Lung Cancer

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🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research

A Data Collection Protocol to Evaluate the Real World Usage of the Orthofix AccelStim Device to Treat Fresh Metatarsal Fractures

Metatarsal Fracture

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🔵 Active, Not Recruiting Phase1 / Phase2 💊 Investigational Drug / Biologic

Effect of Dapagliflozin on Metabolomics and Cardiac Mechanics in Chronic Kidney Disease

Chronic Kidney Diseases

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🔵 Active, Not Recruiting Phase1 / Phase2 💊 Investigational Drug / Biologic

Ultrasound-based Blood-brain Barrier Opening and Albumin-bound Paclitaxel and Carboplatin for Recurrent Glioblastoma

Glioblastoma

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🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program

Optimization of a mHealth Physical Activity Promotion Intervention With Mindful Awareness for AYAO (OPT2MOVE)

Cancer

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🔵 Active, Not Recruiting Phase2 ⚙️ Medical Device Protocol

A Pilot Study Testing Fractional Radiofrequency Versus Fractional Photothermolysis for the Treatment of Acne Scars

Cicatrix

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🔵 Active, Not Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol

Clinical Study of Edwards Cardioband FIT Valve Repair System

Tricuspid Regurgitation

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🔵 Active, Not Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol

PDL and Fractional Photothermolysis for Postsurgical Scars

Scar

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🔵 Active, Not Recruiting Observational / Diagnostic 📋 Clinical Research Protocol

Essential Oils for Electrocautery

Anxiety

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

Alemtuzumab-Ofatumumab in Previously Untreated Symptomatic Chronic Lymphocytic Leukemia

Stage I Chronic Lymphocytic Leukemia

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

Project 1 Aim 2, Adaptations of the Brain in Chronic Pain With Opioid Exposure

Opioid Use

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🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program

Project VIBE: Virtual Intervention for Binge Eating in Adolescents

Obesity

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🔵 Active, Not Recruiting Phase2 📋 Clinical Research Protocol

Resistant Maltodextrin for Gut Microbiome in Parkinson's Disease: Safety and Tolerability Study

Parkinson Disease

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🔵 Active, Not Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol

Transorb™ Self-Gripping Resorbable Mesh in High-risk Subjects Undergoing Open Repair of Ventral Hernia

Hernia

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🔵 Active, Not Recruiting Observational / Diagnostic 📋 Clinical Research Protocol

Utilization of a Web-Based Application to Improve Patient Health Literacy and Reduce Clinic Visit Times in Holmium Laser Enucleation of the Prostate (HoLEP) Procedures and Kidney Stone Surgery

Kidney Stone

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🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program

Optimizing a mHealth Physical Activity Intervention With Mindful Awareness Lessons in Breast Cancer Survivors

Breast Cancer

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🔵 Active, Not Recruiting Phase4 💊 Investigational Drug / Biologic

Erythropoietin Therapy to Induce Regulatory T Cells in Liver Transplant Recipients

Liver Transplant Rejection

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🔵 Active, Not Recruiting Phase4 💊 Investigational Drug / Biologic

Ice Versus EMLA for Pain in Laser Hair Removal

Hair Removal

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🔵 Active, Not Recruiting Phase2 📋 Clinical Research Protocol

Proton Radiation for Stage II/III Breast Cancer

Breast Cancer

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🔵 Active, Not Recruiting Observational / Diagnostic 🩺 Clinical Procedure Protocol

REDUCE Trial- Reducing Prolapse Recurrence

Prolapse; Female

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🔵 Active, Not Recruiting Phase1 / Phase2 💊 Investigational Drug / Biologic

A Study of Tazemetostat With Rituximab and Abbreviated Bendamustine in the Frontline Treatment of High Tumor Burden Follicular Lymphoma

Follicular Lymphoma

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🔵 Active, Not Recruiting Early Phase1 💊 Investigational Drug / Biologic

Effect of Low-Dose Oral Minoxidil as Treatment of Permanent Chemotherapy-Induced Alopecia

Permanent Chemotherapy-induced Alopecia

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🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program

Elements Vital to Treat Obesity Study

Obesity

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🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program

Reducing High-Risk Geriatric Polypharmacy Via EHR Nudges R01 Trial

Polypharmacy

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

Clindamycin and Triamcinolone in People With Glioblastoma to Prevent Skin-Related Side Effects of Tumor Treating Fields

Glioblastoma

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🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program

Promoting Preconception Care and Diabetes Self-Management Among Reproductive-Aged Women With Diabetes

Diabetes Mellitus, Type 2

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🔵 Active, Not Recruiting Observational / Diagnostic 📋 Clinical Research Protocol

Diabetes Toolkit at Discharge

Diabetes Mellitus, Type 2

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🟡 Not Yet Recruiting Phase2 📋 Clinical Research Protocol

Defining the Ablative Dose for Y-90 TARE

HCC - Hepatocellular Carcinoma

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🟡 Not Yet Recruiting Observational / Diagnostic 📋 Clinical Research Protocol

Advanced Robotic Techniques and Rapid Onsite Evaluation for Minimally Invasive Diagnosis and Next-Generation Sequencing.

Peripheral Pulmonary Lesions (PPLs)

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🟡 Not Yet Recruiting Observational / Diagnostic 🩺 Clinical Procedure Protocol

Examining the Effectiveness of DermGEN™ in the Treatment of Diabetic Foot Ulcers in First Nations People

Diabetes Mellitus

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🟡 Not Yet Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol

Use of a Vibration Tool for Postoperative Pain Control in Distal Radius Fractures

Distal Radius Fracture

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🟡 Not Yet Recruiting Early Phase1 💊 Investigational Drug / Biologic

BRIDGE - Blocking Receptor of IL-1β for Donor Graft Edema Reduction

Lung Transplant Recipient

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🟡 Not Yet Recruiting Phase2 💊 Investigational Drug / Biologic

Preoperative Durvalumab, Cisplatin, Gemcitabine With or Without Futibatinib Targeted Therapy for the Treatment of Resectable Intrahepatic Cholangiocarcinoma, OPTIC Trial

Resectable Intrahepatic Cholangiocarcinoma

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🟡 Not Yet Recruiting Phase2 💊 Investigational Drug / Biologic

SMAD4 Tailored Neoadjuvant Therapy for the Treatment of Resectable and Borderline Resectable Pancreatic Ductal Adenocarcinoma, SMART-PANC Trial

Borderline Resectable Pancreatic Ductal Adenocarcinoma

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🟡 Not Yet Recruiting Phase1 / Phase2 💊 Investigational Drug / Biologic

Epidermal Growth Factor Receptor Inhibition for Keratinopathies

Epidermolytic Ichthyosis

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🟡 Not Yet Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program

Healthy Options At Pantries (HOAP) Study

Food Choice

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🟡 Not Yet Recruiting Observational / Diagnostic 📋 Clinical Research Protocol

Personalized Prosthetic Foot Prescription and Rehabilitation for Veterans With Lower Limb Loss

Amputation of Lower Limb

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🟡 Not Yet Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program

Family-Focused Study to Support Medication for Opioid Use Disorder

Opioid Use Disorder

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🟡 Not Yet Recruiting Interventional Protocol 📊 Observational Clinical Research

Implementation of AIP Services for Older Adults With AD

Alzheimer Disease

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🟡 Not Yet Recruiting Phase1 💊 Investigational Drug / Biologic

A Phase I First-in-human Trial of Bvax (B-cell Vaccination) in Addition to Standard of Care Chemoradiotherapy for Newly Diagnosed Glioblastoma

Glioblastoma

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🟡 Not Yet Recruiting Phase1 💊 Investigational Drug / Biologic

Futibatinib With Paclitaxel and Ramucirumab for the Treatment of Locally Advanced or Unresectable Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma

Clinical Stage II Esophageal Adenocarcinoma AJCC v8

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🟡 Not Yet Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program

ALDH2 Genetic Testing in East Asian Community

Healthy Adult

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🟡 Not Yet Recruiting Phase2 💊 Investigational Drug / Biologic

A Study of Weight Loss Intervention With Tirzepatide and Progestin Intrauterine Device to Treat Endometrial Hyperplasia and Grade 1 Endometrial Cancer

Endometrial Atypical Hyperplasia/Endometrioid Intraepithelial Neoplasia

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