52 Recruiting Studies at Ohsu Knight Cancer Institute

Active clinical trials at this research center, sourced directly from the NIH registry.

📍 Portland, Oregon

All research centers

Recruiting Studies at Ohsu Knight Cancer Institute

🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

NeoOPTIMIZE: Early Switching of mFOLFIRINOX or Gemcitabine/Nab-Paclitaxel Before Surgery for the Treatment of Resectable, Borderline Resectable, or Locally-Advanced Unresectable Pancreatic Cancer

Pancreatic Adenocarcinoma

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

Atorvastatin for Preventing Disease Metastasis in Patients With Resected High-Risk Stage IIA, IIB, or IIIA Melanoma

Pathologic Stage IIIA Cutaneous Melanoma AJCC v8

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

Advanced ChemoHormonal Therapy for Treatment Naive Metastatic Prostate Cancer

Castration-Sensitive Prostate Carcinoma

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🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program

War on Melanoma™ Public Health & Education Campaign

Melanoma

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🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program

Electronic Quitline Referral With Enhanced Academic Detailing for the Promotion of Smoking Cessation

Tobacco-Related Carcinoma

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

Isatuximab, Carfilzomib, and Pomalidomide for the Treatment of Relapsed or Refractory Multiple Myeloma

Recurrent Plasma Cell Myeloma

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🔵 Active, Not Recruiting Observational / Diagnostic 📋 Clinical Research Protocol

Decision Aid for the Improvement of Decision-Making in Patients With Non-small Cell Lung Cancer

Lung Non-Small Cell Carcinoma

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🔵 Active, Not Recruiting Early Phase1 💊 Investigational Drug / Biologic

Adavosertib Before Surgery in Treating Patients With Advanced High Grade Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Advanced Fallopian Tube Carcinoma

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🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic

Eribulin and Radiation Therapy in Treating Patients With Retroperitoneal Liposarcoma That Can Be Removed by Surgery

Liposarcoma

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🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic

Entrectinib in Combination With ASTX727 for the Treatment of Relapsed/Refractory TP53 Mutated Acute Myeloid Leukemia

Acute Myeloid Leukemia

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

Pembrolizumab in Treating Patients With Metastatic Castration Resistant Prostate Cancer Previously Treated With Enzalutamide

Castration-Resistant Prostate Carcinoma

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🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program

Standard Verbal Counseling With or Without a Pictorial Educational Tool for the Reduction of Psychological Morbidity in Patients With Stage 0-IIIA Breast Cancer Receiving Radiation Therapy, COPE Study

Anatomic Stage 0 Breast Cancer AJCC v8

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🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic

Venetoclax, Dasatinib, Prednisone, Rituximab and Blinatumomab for the Treatment of Newly Diagnosed or Relapsed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia or Mixed Phenotype Acute Leukemia

B Acute Lymphoblastic Leukemia

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🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research

BEST-RPP Pilot: Screening for Esophageal Cancer in Rural Oregon Without an Endoscopy

Esophageal Cancer

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🔵 Active, Not Recruiting Phase1 / Phase2 💊 Investigational Drug / Biologic

Enzalutamide and Cabazitaxel in Treating Patients With Metastatic, Castration-Resistant Prostate Cancer

Castration-Resistant Prostate Carcinoma

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🟡 Not Yet Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program

Feasibility of an Enhanced Symptom Monitoring and Expedited Subspecialty Care Referral Intervention to Improve Side Effect Management for Patients With Melanoma Receiving an Immune Checkpoint Inhibitor

Melanoma

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🟡 Not Yet Recruiting Phase1 / Phase2 🩺 Clinical Procedure Protocol

A Surgical Procedure (Total Pancreatectomy) With a Transplant Procedure (Islet Cell Autotransplantation) for the Treatment of Chronic Pancreatitis and Benign Pancreatic Tumors

Benign Pancreatic Neoplasm

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🟡 Not Yet Recruiting Phase2 💊 Investigational Drug / Biologic

Mammogram Pretreatment With Ulipristal Acetate

Mammography Screening

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🟡 Not Yet Recruiting Observational / Diagnostic 📋 Clinical Research Protocol

Peer Support Program for Improving Quality of Life Among Head and Neck Patients, Connecting Through Cancer Trial

Malignant Head and Neck Neoplasm

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🟡 Not Yet Recruiting Phase2 💊 Investigational Drug / Biologic

Safety and Efficacy of a Single Dose of Gruticibart to Prevent CRT

Thrombosis

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🟡 Not Yet Recruiting Observational / Diagnostic 📋 Clinical Research Protocol

Phase I Randomized Controlled Trial of Functional Resistance Training in Older Cancer Survivors: The ACES Trial

Hematopoietic and Lymphatic System Neoplasm

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🟡 Not Yet Recruiting Phase2 💊 Investigational Drug / Biologic

Y-90 Radioembolization, Durvalumab, Tremelimumab, and Zanzalintinib for the Treatment of Unresectable and Locally-Advanced Hepatocellular Carcinoma

Locally Advanced Hepatocellular Carcinoma

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🟢 Recruiting Phase2 💊 Investigational Drug / Biologic

Amiodarone for the Prevention of Atrial Fibrillation After Minimally Invasive Esophagectomy in Patients With Esophageal Cancer

Atrial Fibrillation

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🟢 Recruiting Phase4 💊 Investigational Drug / Biologic

Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT Study

Advanced Biliary Tract Carcinoma

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🟢 Recruiting Early Phase1 💊 Investigational Drug / Biologic

OMO-103 for the Treatment of Locally Advanced or Metastatic Pancreatic Ductal Adenocarcinoma

Locally Advanced Pancreatic Ductal Adenocarcinoma

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🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research

Observational Study of Sex Differences in Symptoms During Immune Checkpoint Inhibitor Treatment for People With Cancer

Hematopoietic and Lymphatic System Neoplasm

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🟢 Recruiting Observational / Diagnostic 🩺 Clinical Procedure Protocol

Impact of Dietary Fiber Supplementation on Colonic Microbiome

Benign Colorectal Neoplasm

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🟢 Recruiting Observational / Diagnostic 🩺 Clinical Procedure Protocol

An Exercise Intervention for Improving Mental and Physical Health in Patients With Primary Brain Tumors and Their Caregivers, ET-NEURO Trial

Primary Brain Neoplasm

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🟢 Recruiting Phase2 💊 Investigational Drug / Biologic

Olanzapine for the Management of Cancer Associated Appetite Loss in Patients With Advanced Esophagogastric, Hepatopancreaticobiliary, Colorectal or Lung Cancer

Advanced Malignant Solid Neoplasm

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🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research

Establishing a ctDNA Biomarker to Improve Organ Preserving Strategies in Patients With Rectal Cancer

Rectal Adenocarcinoma

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🟢 Recruiting Observational / Diagnostic 📋 Clinical Research Protocol

Internet-Based Lifestyle Intervention to Eradicate Obese Frailty in Prostate Cancer Survivors, iLIVE

Prostate Carcinoma

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🟢 Recruiting Phase1 / Phase2 💊 Investigational Drug / Biologic

Glofitamab Plus Ibrutinib With Obinutuzumab for the Treatment of Patients With Mantle Cell Lymphoma, IGNITE MCL Trial

Mantle Cell Lymphoma

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🟢 Recruiting Phase4 💊 Investigational Drug / Biologic

Evaluation of the Change in PSMA Expression in Prostate Cancer in Response to Hormonal Therapy

Castration Resistant Prostate Cancer

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🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research

Tumor-informed ctDNA in Muscle-invasive Bladder Cancer for Evaluation of Residual/Recurrent Disease - the TiMBER Trial

Muscle Invasive Bladder Urothelial Carcinoma

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🟢 Recruiting Phase1 💊 Investigational Drug / Biologic

Pemigatinib After Chemotherapy for the Treatment of Newly Diagnosed Acute Myeloid Leukemia

Acute Myeloid Leukemia

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🟢 Recruiting Early Phase1 💊 Investigational Drug / Biologic

Targeted Pathway Inhibition in Patients With Pancreatic Cancer

Locally Advanced Pancreatic Ductal Adenocarcinoma

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🟢 Recruiting Phase2 💊 Investigational Drug / Biologic

Feasibility of FMISO in Brain Tumors

Malignant Brain Neoplasm

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🟢 Recruiting Phase1 💊 Investigational Drug / Biologic

Ruxolitinib With Azacitidine Maintenance for the Treatment of Patients With Acute Myeloid Leukemia Undergoing Reduced Intensity Allogeneic Stem Cell Transplantation

Acute Myeloid Leukemia

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🟢 Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program

A Tailored, Web-based Program (COMPASS) to Improve Exercise and Dietary Changes in Stage I-III Pancreatic Cancer Patients Receiving Neoadjuvant Chemotherapy

Stage I Pancreatic Cancer AJCC v8

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🟢 Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program

GET FIT Together: Testing a Socially Enhanced Exercise Program in Older Men With Prostate Cancer

Prostate Carcinoma

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🟢 Recruiting Phase1 / Phase2 💊 Investigational Drug / Biologic

Axatilimab in Combination With Retifanlimab and Paclitaxel for the Treatment of Patients With Advanced or Metastatic Solid Tumors

Advanced Malignant Solid Neoplasm

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🟢 Recruiting Phase2 💊 Investigational Drug / Biologic

177Lu-DOTATATE for the Treatment of Stage IV or Recurrent Breast Cancer

Anatomic Stage IV Breast Cancer AJCC v8

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🟢 Recruiting Phase2 💊 Investigational Drug / Biologic

Gadolinium and Ferumoxytol MRI in Diagnosing Patients With Abnormalities in the Central Nervous System

Central Nervous System Neoplasm

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RECRUITING Interventional Protocol 📊 Observational Clinical Research

Use Of Indocyanine Green In Pancreas Surgery

Pancreatic Carcinoma

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🟢 Recruiting Phase1 💊 Investigational Drug / Biologic

Iadademstat in Combination With Azacitidine and Venetoclax in Treating Newly Diagnosed Acute Myeloid Leukemia

Acute Myeloid Leukemia

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🟢 Recruiting Phase1 / Phase2 💊 Investigational Drug / Biologic

Mosunetuzumab With Chemotherapy for the Treatment of Patients With Untreated C-Myc Rearrangement Positive High Grade B Cell Lymphoma or Diffuse Large B Cell Lymphoma

Diffuse Large B-Cell Lymphoma

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🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research

Vaccine Responses in Patient With Multiple Myeloma and Non-Hodgkin Lymphoma After CAR-T Treatment

Chronic Lymphocytic Leukemia

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🟢 Recruiting Phase1 💊 Investigational Drug / Biologic

Tafasitamab, Acalabrutinib, and Obinutuzumab for the Treatment of Previously Untreated Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma

Chronic Lymphocytic Leukemia

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🟢 Recruiting Phase2 💊 Investigational Drug / Biologic

Intrathecal Cytarabine, Methotrexate, and Hydrocortisone for the Prevention of High-Grade Chimeric Antigen Receptor T-Cell-Associated Neurotoxicity Syndrome

Hematopoietic and Lymphatic System Neoplasm

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🟢 Recruiting Phase2 💊 Investigational Drug / Biologic

Induction and Consolidation With Fludarabine, Cytarabine, Idarubicin, and Venetoclax for the Treatment of Acute Myeloid Leukemia

Acute Myeloid Leukemia

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🟢 Recruiting Phase2 🩺 Clinical Procedure Protocol

EMBRACE: Exercising Together

Breast Carcinoma

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🟢 Recruiting Observational / Diagnostic 🩺 Clinical Procedure Protocol

CREATE: Art for Children With Cancer

Hematopoietic and Lymphatic System Neoplasm

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