42 Recruiting Studies Using Topotecan
Active clinical trials that use this intervention, sourced directly from the NIH registry.
Browse by conditionTrials Using Topotecan
Study Comparing Tarlatamab With Standard of Care Chemotherapy in Relapsed Small Cell Lung Cancer
π University of South Alabama Mitchell Cancer Institute β Mobile, Alabama
Small Cell Lung Cancer (SCLC)
View Study & Checklist βTesting the Combination of Cediranib and Olaparib in Comparison to Each Drug Alone or Other Chemotherapy in Recurrent Platinum-Resistant Ovarian Cancer
π University of Alabama at Birmingham Cancer Center β Birmingham, Alabama
Fallopian Tube Clear Cell Adenocarcinoma
View Study & Checklist βStudy Of Palbociclib Combined With Chemotherapy In Pediatric Patients With Recurrent/Refractory Solid Tumors
π University of Alabama at Birmingham/Children's of Alabama β Birmingham, Alabama
Ewing Sarcoma
View Study & Checklist βA Study of N9 Chemotherapy in Children With Neuroblastoma
π Memorial Sloan Kettering Cancer Center β New York, New York
Neuroblastoma
View Study & Checklist βTesting the Addition of an Anti-cancer Drug, BAY 1895344, to Usual Chemotherapy for Advanced Stage Solid Tumors, With a Specific Focus on Patients With Small Cell Lung Cancer, Poorly Differentiated Neuroendocrine Cancer, and Pancreatic Cancer
π Mayo Clinic Hospital in Arizona β Phoenix, Arizona
Metastatic Lung Small Cell Carcinoma
View Study & Checklist βPhase 2 Study of Alisertib Therapy for Rhabdoid Tumors
π Lucille Packard Children's Hospital at Stanford University Medical Center β Palo Alto, California
Malignant Rhabdoid Tumor
View Study & Checklist βA Study of LY3295668 Erbumine in Participants With Relapsed/Refractory Neuroblastoma
π UCSF Medical Center at Mission Bay β San Francisco, California
Neuroblastoma
View Study & Checklist βPharmacogenomics ANDA SNP Clinical Study - Topotecan and Single Nucleotide Polymorphisms
π Medicine Invention Design Incorporation β Rockville, Maryland
SCLC
View Study & Checklist βStudy to Assess the Efficacy of Rina-S Compared to Treatment of Investigator's Choice in Participants With Platinum Resistant Ovarian Cancer
π Alaska Women's Cancer Care β Anchorage, Alaska
Platinum-resistant Ovarian Cancer
View Study & Checklist βRandomized Trial of Topotecan With M6620, an ATR Kinase Inhibitor, in Small Cell Lung Cancers and Small Cell Cancers Outside of the Lungs
π Los Angeles General Medical Center β Los Angeles, California
Extensive Stage Lung Small Cell Carcinoma
View Study & Checklist βTesting of Tazemetostat in Combination With Topotecan and Pembrolizumab in Patients With Recurrent Small Cell Lung Cancer
π Keck Medicine of USC Koreatown β Los Angeles, California
Extensive Stage Lung Small Cell Carcinoma
View Study & Checklist βTopotecan Hydrochloride and Carboplatin With or Without Veliparib in Treating Advanced Myeloproliferative Disorders and Acute Myeloid Leukemia or Chronic Myelomonocytic Leukemia
π Los Angeles General Medical Center β Los Angeles, California
Acute Myeloid Leukemia
View Study & Checklist βProtocol for the Study and Treatment of Participants With Intraocular Retinoblastoma
π St. Jude Children's Research Hospital β Memphis, Tennessee
Retinoblastoma
View Study & Checklist βSorafenib and Cyclophosphamide/Topotecan in Patients With Relapsed and Refractory Neuroblastoma
π Children's Hospital Los Angeles β Los Angeles, California
Neuroblastoma
View Study & Checklist βSafety, Preliminary Effectiveness of BNT327, an Investigational Therapy for Patients With Small-cell Lung Cancer in Combination With Chemotherapy
π Alaska Oncology and Hematology, LLC β Anchorage, Alaska
Extensive-stage Small-cell Lung Cancer
View Study & Checklist βVeliparib and Topotecan Hydrochloride in Treating Patients With Solid Tumors, Relapsed or Refractory Ovarian Cancer, or Primary Peritoneal Cancer
π Mayo Clinic Hospital in Arizona β Phoenix, Arizona
Metastatic Malignant Solid Neoplasm
View Study & Checklist βDAREONβ’-9: A Study to Test How Well Different Doses of BI 764532 Are Tolerated by People With Small Cell Lung Cancer When Taken Together With a Single Agent Chemotherapy
π MedStar Georgetown University Hospital β Washington D.C., District of Columbia
Small Cell Lung Carcinoma (SCLC)
View Study & Checklist βComparison of Standard of Care Treatment With a Triplet Combination of Targeted Immunotherapeutic Agents
π Anchorage Associates in Radiation Medicine β Anchorage, Alaska
Fallopian Tube Mucinous Adenocarcinoma
View Study & Checklist βA Study to Compare Sacituzumab Tirumotecan (MK-2870) Monotherapy Versus Treatment of Physician's Choice as Second-line Treatment for Participants With Recurrent or Metastatic Cervical Cancer (MK-2870-020/TroFuse-020/Gog-3101/ENGOT-cx20)
π USA Mitchell Cancer Institute-Clinical Trials ( Site 4126) β Mobile, Alabama
Cervical Cancer
View Study & Checklist βN10: A Study of Reduced Chemotherapy and Monoclonal Antibody (mAb)-Based Therapy in Children With Neuroblastoma
π Memorial Sloan Kettering Cancer Center β New York, New York
High-risk Neuroblastoma
View Study & Checklist βA Study of Combination Chemotherapy for Patients With Newly Diagnosed DAWT and Relapsed FHWT
π Children's Hospital of Alabama β Birmingham, Alabama
Anaplastic Kidney Wilms Tumor
View Study & Checklist βTargeting Pediatric Brain Tumors and Relapsed/Refractory Solid Tumors With Sodium Glucose Cotransporter 2 Inhibitors (SGLT2i)
π Washington University School of Medicine/St. Louis Children's Hospital β St Louis, Missouri
Pediatric Brain Tumor
View Study & Checklist βA Study to Investigate Mocertatug Rezetecan Compared With Standard of Care in Participants With Platinum-resistant Ovarian Cancer (BEHOLD-Ovarian01)
π GSK Investigational Site β Randwick, New South Wales
Ovarian Neoplasms
View Study & Checklist βA Study of Peluntamig (PT217) in Patients With Neuroendocrine Carcinomas Expressing DLL3 (the SKYBRIDGE Study)
π City of Hope (City of Hope National Medical Center, City of Hope Medical Center) β Duarte, California
Small Cell Lung Cancer (SCLC)
View Study & Checklist βMolecular and Clinical Risk-Directed Therapy for Infants and Young Children With Newly Diagnosed Medulloblastoma
π Lucille Packard Children's Hospital Stanford β Palo Alto, California
Medulloblastoma
View Study & Checklist βStudy of NMS-03305293 in Adult Patients With Relapsed Ovarian Cancer
π OSF Saint Francis Medical Center β Peoria, Illinois
Ovarian Cancer
View Study & Checklist βChronic CED of TPT for Recurrent Malignant Glioma
π Columbia University Irving Medical Center / NewYork-Presbyterian Hospital β New York, New York
Brain Tumor, Recurrent
View Study & Checklist βTesting the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)
π Children's Hospital of Alabama β Birmingham, Alabama
Ganglioneuroblastoma
View Study & Checklist βDinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma
π Children's Hospital of Alabama β Birmingham, Alabama
Ganglioneuroblastoma, Nodular
View Study & Checklist βA Study of Ifinatamab Deruxtecan Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung Cancer
π Highlands Oncology Group β Springdale, Arkansas
Small Cell Lung Cancer
View Study & Checklist βA Study of Raludotatug Deruxtecan (R-DXd) in Subjects With Platinum-resistant, High-grade Ovarian, Primary Peritoneal, or Fallopian Tube Cancer
π Alaska Women's Cancer Care β Anchorage, Alaska
Solid Cancer
View Study & Checklist βEflornithine (DFMO) for Ewing Sarcoma and Osteosarcoma
π St. Joseph's Children's Hospital β Tampa, Florida
Osteosarcoma
View Study & Checklist βMetastatic Ewing's Trial Testing Schedule Enhancement to Improve Outcomes
π University of Alabama at Birmingham (Children's of Alabama) β Birmingham, Alabama
Metastatic Ewing Sarcoma
View Study & Checklist βPilot Study of IT Topotecan and Maintenance Chemotherapy for HR-EBTs in Children < 6 Years, Post Consolidation
π Alberta Children's Hospital β Calgary, Alberta
CNS Embryonal Tumor
View Study & Checklist βTesting a Standardized Approach to Surgery and Chemotherapy for Type I Pleuropulmonary Blastoma or the Addition of an Anti-cancer Drug, Topotecan, to the Usual Treatment for Types II and III Pleuropulmonary Blastoma
π Children's Hospital of Alabama β Birmingham, Alabama
Pleuropulmonary Blastoma
View Study & Checklist βStudy of Sacituzumab Govitecan Versus Standard of Care in Participants With Previously Treated Extensive Stage Small Cell Lung Cancer
π Alaska Oncology and Hematology β Anchorage, Alaska
Extensive Stage Small Cell Lung Cancer (ES-SCLC)
View Study & Checklist βA Study of GSK5764227 in Participants With Relapsed Small Cell Lung Cancer (SCLC)
π GSK Investigational Site β Mar del Plata, Buenos Aires
Neoplasms, Lung
View Study & Checklist βAZD5335 vs. Mirvetuximab Soravtansine in FRΞ±-high and AZD5335 vs. Chemotherapy in FRΞ±-low Platinum-resistant Ovarian Cancer
π Research Site β Birmingham, Alabama
Epithelial Ovarian Cancer
View Study & Checklist βA Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer
π University of Alabama at Birmingham β Birmingham, Alabama
Ovarian Neoplasms
View Study & Checklist βDose Attenuated Chemotherapy in Compromised Patients With Lung Cancer
π Fox Chase Cancer Center β Philadelphia, Pennsylvania
Lung Cancer
View Study & Checklist βStudy of Talazoparib in Combination With Chemotherapy in Relapsed Pediatric AML to Determine Safety and Efficacy
π Phoenix Children's Hospital β Phoenix, Arizona
Acute Myeloid Leukemia
View Study & Checklist βA Study to Evaluate Adverse Events and Change in Disease Activity of Intravenous ABBV-706 Versus Standard of Care in Adult Participants With Relapsed/Refractory Small Cell Lung Cancer
π Birmingham Hematology and Oncology Associates d/b/a Alabama Oncology /ID# 280063 β Birmingham, Alabama
Small Cell Lung Cancer
View Study & Checklist β