164 Recruiting Major Depressive Disorder Clinical Trials
Explore open interventional and observational research studies actively enrolling participants across the USA. Verify eligibility and contact site coordinators directly.
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Top Recruiting Major Depressive Disorder Studies
Multi-site Feasibility of an Integrated Treatment for the Biology and Experience of Depression: The MULTIBED Study
📍 University of California, San Francisco, Osher Center for Integrative Health — San Francisco, California
View Study & Checklist ➔Beyond Monoamines: The Role of the Nociceptin/Orphanin FQ Receptor in Major Depression
📍 McLean Hospital — Belmont, Massachusetts
View Study & Checklist ➔Neural-Derived Plasma Exosomal MicroRNAs As Promising Novel Biomarkers for Suicidality and Treatment Outcome in Adolescents
📍 University of Alabama at Birmingham — Birmingham, Alabama
View Study & Checklist ➔Measuring Psychomotor Response to L-DOPA Challenge As a Biomarker for Outcomes in Late-Life Depression: a Pilot Feasibility Trial
📍 St. Paul's Hospital — Vancouver, British Columbia
View Study & Checklist ➔Fisher Wallace Neurostimulation & Depression Study
📍 ProofPilot (Remote Virtual Trial) — New York, New York
View Study & Checklist ➔RESISTance Exercise for Depression Trial
📍 Iowa State University — Ames, Iowa
View Study & Checklist ➔Early Brainwave Biomarkers for Personalized Neuromodulation in Treatment-resistant Depression
📍 Stanford University — Stanford, California
View Study & Checklist ➔Glutamatergic Adaptation to Stress as a Mechanism for Anhedonia and Treatment Response With Ketamine
📍 Emory University — Atlanta, Georgia
View Study & Checklist ➔DBS for TRD With the Medtronic Percept PC
📍 Icahn School of Medicine at Mount Sinai, Mount Sinai West — New York, New York
View Study & Checklist ➔Targeting Network Dysfunction in Apathy of Late-life Depression Using Digital Therapeutics
📍 AdventHealth Neuroscience Institute — Orlando, Florida
View Study & Checklist ➔Study to Assess the Safety and Effectiveness of NMRA-335140-501
📍 Neumora Investigator site — Huntsville, Alabama
View Study & Checklist ➔Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder
📍 University of Alabama at Birmingham — Birmingham, Alabama
View Study & Checklist ➔Neural Circuit Effects of Ketamine in Depression
📍 Icahn School of Medicine at Mount Sinai — New York, New York
View Study & Checklist ➔Neurobehavioral Therapy For Epilepsy And Major Depressive Disorder
📍 Michael E. DeBakey VA Medical Center — Houston, Texas
View Study & Checklist ➔Effects of Intravenous (IV) Citalopram Hydrochloride During Transcranial Magnetic Stimulation in Major Depressive Disorder (MDD)
📍 UCLA Depression Research and Clinic Program — Los Angeles, California
View Study & Checklist ➔Interleaved TMS-fMRI in Ultra-treatment Resistant Depression
📍 Sunnybrook Health Sciences Centre — Toronto, Ontario
View Study & Checklist ➔Maintenance rTMS for Depression (Maitr-De)
📍 University of California, San Diego — San Diego, California
View Study & Checklist ➔Accelerated Intermittent Theta Burst in Treatment-Naive Adolescents
📍 Dell Medical School at University of Texas at Austin — Austin, Texas
View Study & Checklist ➔Regulation of Affect and Physiology in Depression
📍 University of Southern California — Los Angeles, California
View Study & Checklist ➔Taking Action for College Students
📍 Temple University — Philadelphia, Pennsylvania
View Study & Checklist ➔DBS for Depression
📍 University of Texas Southwestern — Dallas, Texas
View Study & Checklist ➔Psilocybin-Assisted Psychotherapy for Treatment-Resistant Depression: Comparing One Versus Two Doses of Psilocybin
📍 Toronto Western Hospital — Toronto, Ontario
View Study & Checklist ➔Psilocybin - Induced Neuroplasticity in the Treatment of Major Depressive Disorder
📍 VA Connecticut Healthcare System, West Haven Campus — West Haven, Connecticut
View Study & Checklist ➔Fixed Order, Open-Label, Dose-Escalation Study of DMT in Humans
📍 Biological Studies Unit at the VA Connecticut Healthcare System, Yale School of Medicine — West Haven, Connecticut
View Study & Checklist ➔Individualized Targeting and Neuromodulation of Late-Life Depression
📍 University of New Mexico HSC — Albuquerque, New Mexico
View Study & Checklist ➔Stress Dynamics and Familial Risk for Depression in Female Adolescents
📍 McLean Hospital — Belmont, Massachusetts
View Study & Checklist ➔Closed-Loop Deep Brain Stimulation for Major Depression
📍 University of California, San Francisco — San Francisco, California
View Study & Checklist ➔In-patient SCC TMS
📍 UCLA TMS Service and Research Service — Los Angeles, California
View Study & Checklist ➔Accelerated TMS for MDD
📍 Brighter Neurotherapeutics — New York, New York
View Study & Checklist ➔Study of ALTO-300 in MDD
📍 Site 200 — Phoenix, Arizona
View Study & Checklist ➔A Phase I/II Study of PDC-1421 for Treating Depression in Cancer Patients
📍 Cedars-Sinai Health System — Los Angeles, California
View Study & Checklist ➔Psilocybin Treatment of Major Depressive Disorder With Co-occurring Alcohol Use Disorder
📍 Johns Hopkins Center for Psychedelic and Consciousness Research — Baltimore, Maryland
View Study & Checklist ➔Ketamine Associated ACC GABA and Glutamate Change and Depression Remission:
📍 Mayo Clinic in Rochester — Rochester, Minnesota
View Study & Checklist ➔Psilocybin With Pimavanserin Compared to Psilocybin Alone for the Treatment of Major Depressive Disorder
📍 Icahn School of Medicine at Mount Sinai, Center for Psychedelic Therapy Research — New York, New York
View Study & Checklist ➔NBI-1065845-MDD3025: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
📍 Neurocrine Clinical Site — Huntsville, Alabama
View Study & Checklist ➔Targeting Large-scale Networks in Depression With Real-time Functional Magnetic Resonance Imaging (fMRI) Neurofeedback
📍 University of Michigan — Ann Arbor, Michigan
View Study & Checklist ➔Imaging SV2A in Mood Disorders
📍 PET Center — New Haven, Connecticut
View Study & Checklist ➔Study of ABX-002 for the Adjunctive Treatment of Major Depressive Disorder (AMPLIFY)
📍 Autobahn Site #131 — Birmingham, Alabama
View Study & Checklist ➔Xenon Inhalation Therapy for Major Depressive Disorder and Bipolar Disorder
📍 Dauten Family Center for Bipolar Treatment Innovation — Boston, Massachusetts
View Study & Checklist ➔Multi-Omic, Clinomic and Digitomic Attributes of Major Depression for Integrative Analytics
📍 Mayo Clinic Florida — Jacksonville, Florida
View Study & Checklist ➔